Effects of uterine and lactational exposure to di-(2-ethylhexyl) phthalate on spatial memory and NMDA receptor of hippocampus in mice.

Chronic Effects of Di(2-ethylhexyl)phthalate on Stereological Parameters of Testis in Adult Wistar Rats

Objective(s) In recent years concerns have been raised regarding the incidence of male reproductive disorders from exposure to endocrine disruptors. So, chronic effects of di(2-ethylhexyl)phthalate were studied on histological and stereological structure of testis in adult Wistar rats. Materials and Methods Thirty two adult Wistar rats were randomly divided in four equal experiment groups; o...

Prevention of di (2-ethylhexyl) Phthalate-induced Testicular Disturbance in Mice by Co-administration of L-carnitine

The Effect of Di-(2-Ethylhexyl) Phthalate (DEHP) on Mouse Daily Sperm Production and Epididymal Sperm Parameters

Purpose: The purpose of this study is to evaluate the effect of Di-(2-ethylhexyl) phthalate (DEHP) on testicular spermatid number per gram testis (TSN), daily sperm production (DSP), count, motility, viability, morphology, and chromatine quality of epididymal sperm. Materials and Methods: The protocol for DEHP administration was that adult male NMRI mice (the age group of 4 weeks) received 29 D...

The effects of gestational and lactational exposure to Nonylphenol on c-jun, and c-fos expression and learning and memory in hippocampus of male F1 rat

Objective(s): To investigate the effects of Nonylphenol (NP) in pups from dams exposed during gestational and lactational periods on immediate early genes (c-jun, c-fos) in hippocampus and the learning and memory of F1 rats. Materials and Methods: Twenty eight pregnant dams, stratified by pregnancy date, were randomly assigned into 4 groups, which were gavaged with NP at the doses of 50 mg/kg/d...

The role of hippocampal (CA1) NMDA receptor on learning and memory in presence and absence of zinc chloride in adult male rats

Introduction: Zinc is an essential trace element that plays an important role in synaptic plasticity and modulating the activity of CNS and involve in learning and memory. Synaptic vesicle zinc in the hippocampus area exerting modulatory effects on NMDA glutamate receptor. Method: In this experiment the effects of NMDA agonist and antagonist administration intra hippocampus on passive avoidan...